Epinephrine vasodilation

Epinephrine is a medication used to treat asthma in adults and children and to improve the symptoms of nasal congestion. Epinephrine causes vasodilation, or widening of blood vessels in the airways, which helps to reduce the swelling, mucus, and congestion of the airways.

Epinephrine is not an FDA-approved treatment for nasal congestion.

Side effects of epinephrine

Epinephrine may cause a fast heart rate and other side effects. These side effects are more common in patients who use this medication for a long time.

These side effects include

  • Fast heart rate
  • Flushing
  • Headache
  • Nasal congestion
  • Runny nose
  • Sweating
  • High blood pressure

Epinephrine is not available in the United States.

What is the dosage of epinephrine nasal spray?

The dosage of epinephrine nasal spray is based on your age, the severity of your symptoms, and the drug form you use.

  • Epinephrine nasal spray is available as a liquid solution.
  • Epinephrine nasal spray is available as a foam.

The usual dosage of epinephrine nasal spray for adults and children is:

  • 0.25 milligrams (mg) for mild symptoms
  • 0.5 mg for moderate symptoms
  • 1 mg for severe symptoms

The maximum dosage is 2 mg.

The usual dosage of epinephrine nasal spray for children under 12 years old is:

  • 0.25 mg for mild symptoms
  • 1 mg for severe congestion
  • 2 mg for moderate congestion

The maximum dosage is 4 mg.

Epinephrine nasal spray may be used together with other medications. Your doctor may adjust your dosage of epinephrine nasal spray based on your medical condition.

You may need to use this medication more often than the dosage on the package label. Follow your doctor’s instructions carefully.

If you have any questions, ask your doctor or pharmacist.

What to do if you miss a dose: If you miss a dose, use it as soon as you can. If it’s close to the time for your next dose, skip the missed dose and go back to your normal dosing schedule.

How to tell if the dosage is correct: The correct dosage is based on your age, medical condition, and other medications you may be taking.

Use the medicine exactly as directed. Do not increase your dose, and do not use more of this medication than called for. Do not use this medication in larger or smaller amounts, or for longer than recommended.

This medication can increase your blood pressure. If you have high blood pressure, tell your doctor before you use this medication.

This medication can lower your blood sugar levels. Tell your doctor if you have diabetes or if you are using a medication to treat this condition.

This medication can cause a false positive result on a drug test. Tell your doctor if you take a drug test.

Tell your doctor if your symptoms do not improve or if they get worse.

Side effects not listed above may be signs of a more serious condition. Tell your doctor if you have any side effect that bothers you or that does not go away.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1800FDA-1088.

Pregnancy Category C

Animal studies have not been conducted with epinephrine nasal spray. It should not be used in women who are pregnant. It may harm the unborn baby.

It is not known whether epinephrine nasal spray will harm an unborn baby when used during pregnancy. Talk to your doctor if you’re pregnant or plan to become pregnant.

It is not known whether epinephrine nasal spray passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Interactions

Epinephrine nasal spray may interact with other medications

You should not use this medication if you are allergic to epinephrine or if you have severe breathing problems.

This drug should not be used with other drugs that cause low blood pressure.

It may also interact with other medications, vitamins, and herbs you may be taking. Different interactions can cause different effects. For instance, some may be harmful, while others may not be.

Some examples of other drugs that can interact with epinephrine nasal spray include:

  • Citalopram
  • Fentanyl
  • Meclizine
  • Pimozide
  • Phenothiazines
  • Sedating antihistamines

Tell your doctor and pharmacist about all your other medications, vitamins, or herbs. You may need to stop using some of them before you start using epinephrine nasal spray.

For example, if you take a potassium supplement, it may interfere with epinephrine nasal spray.

This list is not complete. Other drugs, herbs, and vitamins can affect epinephrine nasal spray, and some may not work or may be dangerous to use with it.

Where can you get epinephrine nasal spray?

Epinephrine nasal spray is available as a prescription. Your doctor will determine the best dosage and the form of the medication for you.

The form of epinephrine nasal spray you get depends on the pharmacy you use. You may be able to fill your prescription at a retail pharmacy or a mail-order pharmacy.

You should not use this medication if you have ever had an allergic reaction to epinephrine or if you have a severe allergy to it.

You should also not use it if you are allergic to any of its ingredients.

You should not use epinephrine nasal spray if you are pregnant.

When should I not use epinephrine nasal spray?

Do not use epinephrine nasal spray if you have used an antihistamine within the past 24 hours or if you have a severe allergic reaction to it.

Do not use this medication if you are allergic to epinephrine or if you have a severe allergic reaction to it or if you have heart problems.

In conclusion

Epinephrine nasal sprays are available over the counter without a doctor’s prescription. They are also available as a prescription.

The dosage you need will depend on your condition, the form of the medication you use, and other medications you may be taking.

If you have any new or different symptoms, talk to your doctor or pharmacist.

Epinephrine nasal sprays are not recommended for use in people younger than 6 years old.

The safety and effectiveness of this medication depend on several factors. Using it correctly can affect your condition and how well it works.

Before taking this medication, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Also tell them about any vitamins or supplements you are taking. Sharing this information can help you avoid potential interactions.

Do not use this medication if you have ever had an allergic reaction to epinephrine or if you have a severe allergic reaction to it.

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